Linked Life Data

2335398

Source:http://linkedlifedata.com/resource/pubmed/id/2335398

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-6-8
pubmed:abstractText
Biopsies isolated from various human stratified epitheliomas and cultures of the associated fibroblasts exhibit a breakdown in catalase activity (70 to 95%). We report here that primary human cultures of keratinocytes and various immortalized keratinocyte cell lines differ from one other in their catalase activity. Moreover, deficient catalase activity appears to be related to the intensity of tumor phenotype expression. Since catalase activity in cell lines transformed in vitro is not as weak as activity observed in cell lines isolated from tumors, catalase deficiency may follow the successive steps of tumor progression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0020-7136
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
952-6
pubmed:dateRevised
2007-7-24
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Deficiency in catalase activity correlates with the appearance of tumor phenotype in human keratinocytes.
pubmed:affiliation
Biochimie et Physiologie du développement CNRS URA686, Département de Biologie, Ecole Normale Supérieure, Paris, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't