Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1990-6-7
|
| pubmed:abstractText |
Ten obese non-insulin-dependent diabetics (six men, four women) with secondary drug failure were treated with a hypocaloric diet only (2100-3350 kJ/d) for 3 mo to assess the effects of weight reduction on metabolic control, energy production rate, and cardiovascular risk factors. During the 3 mo of follow-up the mean body weight decreased from 101.0 +/- 7.2 (means +/- SEM) to 87.2 +/- 5.5 kg (p less than 0.001). Basal energy production rate (kJ/min) decreased by 8.5%. Fasting blood glucose declined from 12.3 +/- 0.4 to 10.5 +/- 0.7 mmol/L (p less than 0.05) but mean diurnal glucose and glycosylated hemoglobin A1c did not change significantly. Serum total cholesterol was decreased at 2 wk but at 3 mo it did not differ significantly from the baseline value. A marked reduction was observed in serum triglycerides after 3 mo (4.57 +/- 1.0 vs 2.18 +/- 0.26 mmol/L, p = 0.012). The high-density lipoprotein (HDL) cholesterol increased after weight reduction (0.96 +/- 0.06 vs 1.11 +/- 0.05 mmol/L, p = 0.009). A significant decline was found in both systolic (152 +/- 6 vs 133 +/- 3 mm Hg, p = 0.004) and diastolic blood pressure (92 +/- 3 vs 81 +/- 3 mm Hg, p = 0.007). There was no evidence of linoleic acid deficiency after this diet.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0002-9165
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
51
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
768-73
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2333833-Adult,
pubmed-meshheading:2333833-Blood Glucose,
pubmed-meshheading:2333833-Blood Pressure,
pubmed-meshheading:2333833-Body Weight,
pubmed-meshheading:2333833-Calorimetry, Indirect,
pubmed-meshheading:2333833-Cholesterol,
pubmed-meshheading:2333833-Coronary Disease,
pubmed-meshheading:2333833-Diabetes Complications,
pubmed-meshheading:2333833-Diabetes Mellitus,
pubmed-meshheading:2333833-Diabetes Mellitus, Type 2,
pubmed-meshheading:2333833-Diet, Reducing,
pubmed-meshheading:2333833-Electrocardiography,
pubmed-meshheading:2333833-Energy Intake,
pubmed-meshheading:2333833-Female,
pubmed-meshheading:2333833-Humans,
pubmed-meshheading:2333833-Hypertension,
pubmed-meshheading:2333833-Male,
pubmed-meshheading:2333833-Middle Aged,
pubmed-meshheading:2333833-Obesity,
pubmed-meshheading:2333833-Risk Factors,
pubmed-meshheading:2333833-Vectorcardiography
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Effects of a very-low-calorie diet on metabolic control and cardiovascular risk factors in the treatment of obese non-insulin-dependent diabetics.
|
| pubmed:affiliation |
Clinical Nutrition Unit, University of Kuopio, Finland.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|