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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1990-3-26
|
| pubmed:abstractText |
We report here a case of acute nonlymphocytic leukemia evolving from a myelodysplastic syndrome which developed in an elderly man who had received radiation therapy for a prior cancer. Cytogenetic analysis revealed the following karyotype: 47,XY, + 8,t(1;6)(p13;p23). The breakpoints in the translocation are in the regions of the NRAS1 and PIM1 oncogenes on chromosomes 1 and 6, respectively. This translocation has not been previously observed in hematological malignancies.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0165-4608
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
45
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
67-71
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2302687-Aged,
pubmed-meshheading:2302687-Chromosome Banding,
pubmed-meshheading:2302687-Chromosomes, Human, Pair 1,
pubmed-meshheading:2302687-Chromosomes, Human, Pair 6,
pubmed-meshheading:2302687-Humans,
pubmed-meshheading:2302687-Karyotyping,
pubmed-meshheading:2302687-Leukemia, Myeloid, Acute,
pubmed-meshheading:2302687-Leukemia, Radiation-Induced,
pubmed-meshheading:2302687-Male,
pubmed-meshheading:2302687-Neoplasms,
pubmed-meshheading:2302687-Translocation, Genetic
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Translocation (1;6)(p12;p23) in ANLL.
|
| pubmed:affiliation |
Cancer Center, Southwest Biomedical Research Institute, Scottsdale, Arizona 85251.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
|