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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1990-2-7
|
| pubmed:abstractText |
Right ventricular ejection fractions have been difficult to estimate clinically. It has been recently suggested that right ventricular ejection fractions can be calculated by thermodilution techniques with a fast-response thermistor and computer. These studies were performed to compare right ventricular ejection fractions obtained from thermodilution and biplane ventriculography. Ten pigs were instrumented with a right ventricular angiographic, thermodilution, and systemic arterial catheter. Right ventricular ejection fractions were determined by thermodilution and ventriculography at four times: (1) baseline, (2) infusion of isoporterenol (5 micrograms/min), (3) 50% of baseline mean arterial pressure produced by hemorrhage, and (4) reinfusion of isoproterenol during hypovolemia. A significant correlation existed between thermodilution and ventriculographic ejection fractions (r = 0.74, p = 0.004). However, during hypovolemia, thermodilution measurements of right ventricular ejection fraction were significantly lower than ventriculographic measurements (p less than 0.05). To determine if the position of the thermistor had a significant effect on thermodilution computations, right ventricular ejection fractions were computed by thermodilution in 10 additional pigs by means of a jugular and femoral insertion, as well as by ventriculography in each pig. Femoral insertion resulted in a greater distance from pulmonic valve to thermistor as compared with jugular placement (p = 0.005). Right ventricular ejection fractions obtained from femoral placement were significantly less than those obtained by jugular insertion (p = 0.008) and ventriculography (p = 0.006). There was no significant difference between jugular and ventriculographic ejection fractions (p = 0.35). Results from these studies demonstrates that thermodilution right ventricular ejection fraction measurements are strongly correlated to ventriculographic methods over a wide hemodynamic range and that improved accuracy is obtained when the pulmonic valve to thermistor distance is minimized. Thus thermodilution may provide a simple and repeatable means to monitor right ventricular function in the critical care setting.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0022-5223
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
99
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
141-52
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1990
|
| pubmed:articleTitle |
Right ventricular function computed by thermodilution and ventriculography. A comparison of methods.
|
| pubmed:affiliation |
Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston 29425.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|