|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
1991-4-4
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|
pubmed:abstractText |
Loracarbef concentrations in plasma and middle ear fluid (MEF) were measured in specimens obtained approximately 2 h after doses of 7.5 or 15 mg/kg. The mean +/- standard deviation concentrations in MEF were 2.0 +/- 2.6 mg/liter (48% of the concentration in plasma) after the smaller dose and 3.9 +/- 2.6 mg/liter (42% of the concentration in plasma) after the larger dose. With the larger dose, the concentrations in MEF were greater than the MIC for 90% of strains of the usual pathogens of acute otitis media tested in 16 of 17 specimens.
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|
pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0066-4804
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
34
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2030-1
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:2291672-Body Fluids,
pubmed-meshheading:2291672-Cephalosporins,
pubmed-meshheading:2291672-Child,
pubmed-meshheading:2291672-Child, Preschool,
pubmed-meshheading:2291672-Ear, Middle,
pubmed-meshheading:2291672-Female,
pubmed-meshheading:2291672-Humans,
pubmed-meshheading:2291672-Infant,
pubmed-meshheading:2291672-Male,
pubmed-meshheading:2291672-Otitis Media,
pubmed-meshheading:2291672-Tympanoplasty
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|
pubmed:year |
1990
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|
pubmed:articleTitle |
Loracarbef concentrations in middle ear fluid.
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|
pubmed:affiliation |
Department of Otorhinolaryngology University of Texas, Southwestern Medical Center, Dallas 75235.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
