Linked Life Data

2274749

Source:http://linkedlifedata.com/resource/pubmed/id/2274749

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-2-22
pubmed:abstractText
Circulatory changes and renal uptake of free fatty acids (FFA), glycerol and triglycerides were studied in ten adult beagle dogs during pentobarbital anesthesia. Six dogs were injected intravenously with E. coli endotoxin 0.5 mg/kg over 15 min and four control dogs received saline. Cardiac depression, hypotension, renal hypoperfusion and acidosis resulted in endotoxin shock. Arterial FFA concentrations increased significantly 2 hours after onset of shock whereas renal venous FFA levels remained rather stationary during the 5-hour study. Arterial and renal venous glycerol levels increased during the first two hours and decreased thereafter. Unchanged triglyceride levels were observed in endotoxin shock. The renal uptake of FFA increased with increasing arterial FFA concentrations. Net renal uptake of glycerol and triglycerides were observed as well. Blood concentrations and renal uptake of fats and glycerol remained relatively stationary in the control animals through the observation period. These data suggest renal ability to consume FFA, glycerol and triglycerides during endotoxin shock.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0036-5599
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-5
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Renal uptake of fats and glycerol in endotoxin shock in dogs.
pubmed:affiliation
Department of Surgery, University of Turku, Finland.
pubmed:publicationType
Journal Article