rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1991-2-28
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pubmed:abstractText |
We have utilized quantitative autoradiography to define subtypes of 125I-angiotensin II (AII) binding in rat brain. AII-1 binding (displaced by DuP 753) was found in the nucleus of the solitary tract and the hypothalamus, while AII-2 binding (displaced by WL 19) was found in the thalamus and lateral septum. These results indicate that subtypes of the AII receptor are present in the brain and the AII-1 receptor subtype is present in regions consistant with the known actions of angiotensin.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0014-2999
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
187
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
123-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2272349-Angiotensin II,
pubmed-meshheading:2272349-Animals,
pubmed-meshheading:2272349-Autoradiography,
pubmed-meshheading:2272349-Binding, Competitive,
pubmed-meshheading:2272349-Brain,
pubmed-meshheading:2272349-Brain Chemistry,
pubmed-meshheading:2272349-Hypothalamus,
pubmed-meshheading:2272349-Imidazoles,
pubmed-meshheading:2272349-Iodine Radioisotopes,
pubmed-meshheading:2272349-Losartan,
pubmed-meshheading:2272349-Male,
pubmed-meshheading:2272349-Medulla Oblongata,
pubmed-meshheading:2272349-Pyridines,
pubmed-meshheading:2272349-Rats,
pubmed-meshheading:2272349-Rats, Inbred Strains,
pubmed-meshheading:2272349-Receptors, Angiotensin,
pubmed-meshheading:2272349-Tetrazoles
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pubmed:year |
1990
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pubmed:articleTitle |
Non-peptide angiotensin II receptor antagonists discriminate subtypes of 125I-angiotensin II binding sites in the rat brain.
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pubmed:affiliation |
Central Nervous System and Cardiovascular Research, Eli Lilly and Company, Indianapolis, IN 46285.
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pubmed:publicationType |
Journal Article
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