Linked Life Data

2272091

Source:http://linkedlifedata.com/resource/pubmed/id/2272091

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1991-2-25
pubmed:abstractText
It has been suggested that histamine plays an important role in the pathogenesis of cluster headache. In addition, both neurogenic and vascular components have been described during cluster headache attacks without an obvious anatomical link between them. Our ultrastructural observations of human temporal arteries from cluster headache patients and their comparison to those from a control group strongly suggest that mast cells may be this link. Mast cells in both groups show a very close apposition with nerve fibres, suggesting a functional interaction between them. Moreover, in the cluster headache group exclusively, adventitial mast cells show profound morphological modifications suggesting progressive degranulation. These data strongly suggest that mast cells could be directly or indirectly involved in the pathophysiology of cluster headaches.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0333-1024
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-8
pubmed:dateRevised
2008-2-11
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Cluster headache: ultrastructural evidence for mast cell degranulation and interaction with nerve fibres in the human temporal artery.
pubmed:affiliation
Université Paris VII, INSERM U182, CNRS UA641, Paris, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't