Linked Life Data

2253957

Source:http://linkedlifedata.com/resource/pubmed/id/2253957

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1991-1-24
pubmed:abstractText
Infiltrated skin lesions, histologically characterized by a perivascular and periadnexal lympho-histiocytic infiltrate in the upper and deep dermis, are quite frequently observed in patients with B-cell chronic lymphocytic leukemia (C-CLL). The correct identification of the actual nature of these lesions, defined as specific on clinical and histologic grounds, is essential for a proper staging of the disease and, consequently, for the prognostic evaluation. In 6 patients with B-CLL, we performed an immunohistochemical study of specific skin lesions, with the aim of exactly defining the actual nature of infiltrating cells. Only in 2 of 6 cases immunophenotyping evidenced the neoplastic B-cell nature of skin infiltrating lymphoid cells; this finding was clearly correlated with the clinical evolution of the disease, rapidly fatal in both cases. The results of the present study indicate that the immunohistochemical analysis of skin lesions allows the proper staging of the disease, thus giving an important prognostic indication.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0026-4741
pubmed:author
pubmed:issnType
Print
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-24
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
["Specific" skin lesions in chronic lymphatic leukemia].
pubmed:affiliation
Clinica Dermatologica II, Università di Firenze.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract