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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-1-9
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pubmed:abstractText |
Alternaria allergens, separated by SDS polyacrylamide gel electrophoresis and transferred onto a nitrocellulose membrane, were identified using sera from Alternaria-allergic patients. 30 Alternaria components of spore and mycelium, ranging in molecular weight from more than 150 to 12 kD, bound IgE antibodies. 15 were detected by more than 25% of the sera and only 4 (85, 56, 42, 31 kD) by more than 50% of the sera. Among these four major allergens, the 56-kD component was present mostly in the spore extract, the 85- and 42-kD fractions in the mycelium extract and the 31-kD in both extracts. The 31-kD component showed the highest IgE binding and the highest frequency of binding (95% with mycelium extract and 79% with spore extract). It was composed of two subunits.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0020-5915
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2246069-Allergens,
pubmed-meshheading:2246069-Alternaria,
pubmed-meshheading:2246069-Animals,
pubmed-meshheading:2246069-Blotting, Western,
pubmed-meshheading:2246069-Humans,
pubmed-meshheading:2246069-Immunoelectrophoresis, Two-Dimensional,
pubmed-meshheading:2246069-Immunoglobulin E,
pubmed-meshheading:2246069-Molecular Weight,
pubmed-meshheading:2246069-Rabbits
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pubmed:year |
1990
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pubmed:articleTitle |
Comparison of conidial and mycelial allergens of Alternaria alternata.
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pubmed:affiliation |
Unité de Mycologie, Institut Pasteur, Paris, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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