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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1990-11-19
|
pubmed:abstractText |
We describe a patient who presented with polyarthritis, pleurisy, rash, and a positive antinuclear antibody result after 5 years of D-penicillamine therapy. D-penicillamine-induced antinuclear antibodies were mainly high-titer IgG directed against the (H2A-H2B)-DNA complex. Weak IgM activity with H1 and H2B was also observed. Withdrawal of D-penicillamine therapy resulted in improvement in clinical symptoms and gradual resolution of serologic abnormalities.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0004-3591
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
33
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1582-5
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading | |
pubmed:year |
1990
|
pubmed:articleTitle |
D-penicillamine-induced lupus erythematosus.
|
pubmed:affiliation |
Rheumatology Service, Fitzsimons Army Medical Center, Aurora, Colorado 80045.
|
pubmed:publicationType |
Journal Article,
Case Reports
|