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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-8-24
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pubmed:databankReference | |
pubmed:abstractText |
Broad-host-range IncP plasmids possess a series of operons involved in plasmid maintenance, whose expression is coordinated by a series of regulators, most of which are encoded in a central regulatory operon. The nucleotide sequence of a new monocistronic operon located between coordinates 55.0 and 56.0 kb on the genome of the IncP alpha plasmids RK2 and RP4 is presented. The operon encodes a 34 kDa protein which has a net negative charge. Transcription of the operon, designated by us kfrA (korF-regulated), is repressed not only by the product of the previously described korA gene but also by the product of a gene which we have designated korF and which has not been described previously. The korF gene is encoded downstream from korB within the key korA/korB regulatory operon. We propose that K or F binds to a novel inverted repeat overlapping the promoter for the kfrA operon.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0378-1119
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
29-35
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2197180-Amino Acid Sequence,
pubmed-meshheading:2197180-Base Sequence,
pubmed-meshheading:2197180-Escherichia coli,
pubmed-meshheading:2197180-Gene Expression Regulation, Bacterial,
pubmed-meshheading:2197180-Genes, Regulator,
pubmed-meshheading:2197180-Molecular Sequence Data,
pubmed-meshheading:2197180-Operon,
pubmed-meshheading:2197180-Plasmids,
pubmed-meshheading:2197180-Promoter Regions, Genetic,
pubmed-meshheading:2197180-Repressor Proteins,
pubmed-meshheading:2197180-Transcription, Genetic,
pubmed-meshheading:2197180-Transcription Factors
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pubmed:year |
1990
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pubmed:articleTitle |
Identification of a seventh operon on plasmid RK2 regulated by the korA gene product.
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pubmed:affiliation |
Department of Biological Sciences, University of Birmingham, U.K.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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