Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1990-8-16
|
pubmed:abstractText |
In the coastal area of Benin, where chloroquine resistant Plasmodium falciparum strains occur, 152 children in the Guezo military camp (Cotonou) and 448 children in a fishermen village (Ekpe), on the southern bank of lake Nokoue, are examined. The falciparum malaria infected children (29 and 135 respectively) have received 35 mg/kg body weight of amodiaquine (Flavoquine) divided in three consecutive daily doses. Only one child among the 69 treated having a parasitemia higher than 1,000/mm3 failed to be cured. The amodiaquine tolerance is excellent for, respectively, 64% and 72% of the children. Minor side-effects are rapidly regressive. The frequency of conjonctival hyperhemia as an amodiaquine side-effect is nevertheless relatively high (14.7%) in the children regularly treated with this drug, e.g. those of the military camp, while it is rare (0.8%) in others, e.g. in the fishermen village children where amodiaquine is unusual as an antimalarial medicine.
|
pubmed:language |
fre
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0025-682X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
50
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
21-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2195282-Adolescent,
pubmed-meshheading:2195282-Amodiaquine,
pubmed-meshheading:2195282-Animals,
pubmed-meshheading:2195282-Benin,
pubmed-meshheading:2195282-Carrier State,
pubmed-meshheading:2195282-Child,
pubmed-meshheading:2195282-Child, Preschool,
pubmed-meshheading:2195282-Drug Resistance,
pubmed-meshheading:2195282-Humans,
pubmed-meshheading:2195282-Malaria,
pubmed-meshheading:2195282-Plasmodium falciparum,
pubmed-meshheading:2195282-Rural Population,
pubmed-meshheading:2195282-Urban Population
|
pubmed:articleTitle |
[In vivo amodiaquine sensitivity of Plasmodium falciparum in the town of Cotonou and in the vicinity (Bénin)].
|
pubmed:affiliation |
Service de Parasitologie, Université de Bordeaux II, France.
|
pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|