Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-8-1
pubmed:abstractText
Allogeneic marrow transplantation has emerged as a curative therapy for many patients with acute leukemia. The ability to cure patients of their disease is dependent on the remission status of the patient. For patients with acute myelogenous leukemia, up to 60% of patients can become long-term, disease-free survivors, whereas a similar number of patients with high-risk acute lymphoblastic leukemia can also achieve cure of their disease. The improved results with marrow transplantation have allowed the application of this therapy for patients up to the age of 50 years. Even patients with therapy-related leukemias can benefit from this approach. Although relapse is still a problem in all remission stages, current studies suggest that improved preparatory regimens, in combination with better treatment of graft-versus-host disease and prevention of cytomegalovirus pneumonia, will continue to improve the overall results of this therapy for patients with acute leukemia.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0889-8588
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
517-33
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Allogeneic bone marrow transplantation for acute leukemia.
pubmed:affiliation
Department of Hematology and Bone Marrow Transplantation, City of Hope National Medical Center, Duarte, California.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review