Linked Life Data

21919375

Source:http://linkedlifedata.com/resource/pubmed/id/21919375

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-9-16
pubmed:abstractText
The Spectral Entropy proposed to monitor the depth of anesthesia includes the State Entropy (SE) computed from the EEG (0.8-32 Hz frequency band), and the Response Entropy (RE) computed from EEG and facial muscles activity (0.5-47 Hz frequency band). We report an unexpected Entropy response to saline spraying at the end of posterior fossa surgery. Six patients undergoing scheduled functional surgery of the posterior fossa were included in this report. They were anesthetized with propofol and remifentanil using TCI and received an intubation dose of rocuronium. At the end of surgery, saline spraying, performed for hemostatic purpose and wreckage elimination, resulted in a sustained increase in RE and SE without hemodynamic modification in four patients, while no change was observed in the two other ones. In one of the responding patients, 0.1 mg kg(-1) rocuronium attenuated the Entropy response. In the two non responders, repetition of spraying or rocuronium administration did not change Entropy value. Recovery from anesthesia was comparable in all patients and none of them complained from awareness. We conclude that Entropy can increase during posterior fossa surgery in non-paralyzed patients. This response probably reflects an increase in facial muscle activity rather than a change in depth of anesthesia, as far as it can be attenuated by a small dose of rocuronium. While this hypothesis requires further investigation, these observations suggest that saline spraying may confound interpretation of Entropy during posterior fossa surgery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5164
pubmed:author
pubmed:issnType
Print
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-90
pubmed:meshHeading
pubmed-meshheading:21919375-Administration, Topical, pubmed-meshheading:21919375-Adult, pubmed-meshheading:21919375-Androstanols, pubmed-meshheading:21919375-Anesthetics, Intravenous, pubmed-meshheading:21919375-Blood Pressure, pubmed-meshheading:21919375-Brain, pubmed-meshheading:21919375-Electroencephalography, pubmed-meshheading:21919375-Entropy, pubmed-meshheading:21919375-Facial Muscles, pubmed-meshheading:21919375-Heart Rate, pubmed-meshheading:21919375-Hemostatic Techniques, pubmed-meshheading:21919375-Humans, pubmed-meshheading:21919375-Monitoring, Intraoperative, pubmed-meshheading:21919375-Neuromuscular Nondepolarizing Agents, pubmed-meshheading:21919375-Piperidines, pubmed-meshheading:21919375-Propofol, pubmed-meshheading:21919375-Sodium Chloride, pubmed-meshheading:21919375-Volatilization
pubmed:year
2011
pubmed:articleTitle
Unexpected entropy response to saline spraying at the end of posterior fossa surgery: a few cases report.
pubmed:affiliation
Department of Anesthesia and ICM, CHR Citadelle, Liege, Belgium.
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't