| pubmed-article:21894764 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21894764 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:21894764 | lifeskim:mentions | umls-concept:C0031327 | lld:lifeskim |
| pubmed-article:21894764 | lifeskim:mentions | umls-concept:C0870883 | lld:lifeskim |
| pubmed-article:21894764 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:21894764 | pubmed:dateCreated | 2011-9-7 | lld:pubmed |
| pubmed-article:21894764 | pubmed:abstractText | Pharmacokinetics of compound M-11 (main metabolite of afobazole) after administration via different routes was studied in rats. After oral and intravenous administration, M-11 exhibited weakly pronounced bioconversion with the formation of a few metabolites that could be detected in plasma samples for about 3 hours. The absolute bioavailability of M-11 after oral administration was 68.3%. It was found that M-11 was completely absorbed from gastrointestinal tract of rats and characterized by "the first pass effect", after which approximately 70% of administered dose entered the circulation. The parent substance was determined neither in urine nor in feces. | lld:pubmed |
| pubmed-article:21894764 | pubmed:language | rus | lld:pubmed |
| pubmed-article:21894764 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21894764 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21894764 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21894764 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21894764 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21894764 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21894764 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21894764 | pubmed:issn | 0869-2092 | lld:pubmed |
| pubmed-article:21894764 | pubmed:author | pubmed-author:ZherdevV PVP | lld:pubmed |
| pubmed-article:21894764 | pubmed:author | pubmed-author:LitvinA AAA | lld:pubmed |
| pubmed-article:21894764 | pubmed:author | pubmed-author:KolyvanovG... | lld:pubmed |
| pubmed-article:21894764 | pubmed:author | pubmed-author:MozhaevaT... | lld:pubmed |
| pubmed-article:21894764 | pubmed:author | pubmed-author:ViglinskaiaA... | lld:pubmed |
| pubmed-article:21894764 | pubmed:author | pubmed-author:BastryginD... | lld:pubmed |
| pubmed-article:21894764 | pubmed:author | pubmed-author:BochkovP OPO | lld:pubmed |
| pubmed-article:21894764 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:21894764 | pubmed:volume | 74 | lld:pubmed |
| pubmed-article:21894764 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21894764 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21894764 | pubmed:pagination | 22-6 | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
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| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:meshHeading | pubmed-meshheading:21894764... | lld:pubmed |
| pubmed-article:21894764 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21894764 | pubmed:articleTitle | [Pharmacokinetics of afobazole metabolite (M-11) in rats]. | lld:pubmed |
| pubmed-article:21894764 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21894764 | pubmed:publicationType | English Abstract | lld:pubmed |
