Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2011-8-11
pubmed:abstractText
Two new triterpenoid saponins 1 and 2, along with six known saponins 3-8, were isolated from the roots of Dipsacus asper. The structures of new compounds were established as 3-O-?-d-glucopyranosyl-(1 ? 4)-[?-l-rhamnopyranosyl-(1 ? 3)]-?-d-glucopyranosyl-(1 ? 3)-?-l-rhamnopyranosyl-(1 ? 2)-?-l-arabinopyranosyl-hederagenin-28-O-?-d-glucopyranoside (dipsacus saponin J, 1) and 3-O-?-l-arabinopyranosyl-hederagenin-28-O-?-d-glucopyranosyl-(1 ? 6)-?-d-glucopyranosyl-(1 ? 6)-?-d-glucopyranoside (dipsacus saponin K, 2). The structures were determined by extensive analysis of their spectroscopic data. Compounds 6 and 7 could significantly stimulate UMR106 cell proliferation and increase alkaline phosphatase activities in UMR106 cell at the concentration of 4 ?M.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1477-2213
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
851-60
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Triterpenoid saponins from Dipsacus asper and their activities in vitro.
pubmed:affiliation
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't