Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2011-8-8
pubmed:abstractText
Objectives. The aim of this study was to assess the effectiveness of SPECT/CT for volume measurements and to report a case illustrating the major impact of SPECT/CT in calculating the vascularized liver volume and dosimetry prior to injecting radiolabelled yttrium-90 microspheres (Therasphere). Materials and Methods. This was a phantom study, involving volume measurements carried out by two operators using SPECT and SPECT/CT images. The percentage of error for each method was calculated, and interobserver reproducibility was evaluated. A treatment using Therasphere was planned in a patient with three hepatic arteries, and the quantitative analysis of SPECT/CT for this patient is provided. Results. SPECT/CT volume measurements proved to be accurate (mean error <6% for volumes ?16?cm(3)) and reproductive (interobserver agreement = 0.9). In the case report, (99m)Tc-MAA SPECT/CT identified a large liver volume, not previously identified with angiography, which was shown to be vascularized after selective MAA injection into an arterial branch, resulting in a large modification in the activity of Therasphere used. Conclusions. MAA SPECT/CT is accurate for vascularized liver volume measurements, providing a valuable contribution to the therapeutic planning of patients with complex hepatic vascularization.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-12354840, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-1327493, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-16002500, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-16085592, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-16923973, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-17204722, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-20080899, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-20708286, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-2549567, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-7493353, http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-7870393
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
2090-1720
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
2011
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
398051
pubmed:year
2011
pubmed:articleTitle
Utility of Quantitative Tc-MAA SPECT/CT for yttrium-Labelled Microsphere Treatment Planning: Calculating Vascularized Hepatic Volume and Dosimetric Approach.
pubmed:affiliation
Department of Nuclear Medicine, Comprehensive Cancer Center Eugène Marquis, CS 44229, 35042 Rennes, France.
pubmed:publicationType
Journal Article