Source:http://linkedlifedata.com/resource/pubmed/id/21822489
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2011-8-8
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pubmed:abstractText |
Objectives. The aim of this study was to assess the effectiveness of SPECT/CT for volume measurements and to report a case illustrating the major impact of SPECT/CT in calculating the vascularized liver volume and dosimetry prior to injecting radiolabelled yttrium-90 microspheres (Therasphere). Materials and Methods. This was a phantom study, involving volume measurements carried out by two operators using SPECT and SPECT/CT images. The percentage of error for each method was calculated, and interobserver reproducibility was evaluated. A treatment using Therasphere was planned in a patient with three hepatic arteries, and the quantitative analysis of SPECT/CT for this patient is provided. Results. SPECT/CT volume measurements proved to be accurate (mean error <6% for volumes ?16?cm(3)) and reproductive (interobserver agreement = 0.9). In the case report, (99m)Tc-MAA SPECT/CT identified a large liver volume, not previously identified with angiography, which was shown to be vascularized after selective MAA injection into an arterial branch, resulting in a large modification in the activity of Therasphere used. Conclusions. MAA SPECT/CT is accurate for vascularized liver volume measurements, providing a valuable contribution to the therapeutic planning of patients with complex hepatic vascularization.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-12354840,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-1327493,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-16002500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-16085592,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-16923973,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-17204722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-20080899,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-20708286,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-2549567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-7493353,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21822489-7870393
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pubmed:language |
eng
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pubmed:journal | |
pubmed:status |
PubMed-not-MEDLINE
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pubmed:issn |
2090-1720
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
2011
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
398051
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pubmed:year |
2011
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pubmed:articleTitle |
Utility of Quantitative Tc-MAA SPECT/CT for yttrium-Labelled Microsphere Treatment Planning: Calculating Vascularized Hepatic Volume and Dosimetric Approach.
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pubmed:affiliation |
Department of Nuclear Medicine, Comprehensive Cancer Center Eugène Marquis, CS 44229, 35042 Rennes, France.
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pubmed:publicationType |
Journal Article
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