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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2011-8-18
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pubmed:abstractText |
Serial dopamine transporter (DAT) imaging in patients with Parkinson's disease (PD) and other synucleinopathies shows progressive nigrostriatal dopaminergic dysfunction. Because idiopathic rapid-eye-movement (REM) sleep behaviour disorder (IRBD) can precede the classic symptoms of PD and other synucleinopathies, we postulated that serial DAT imaging in patients with IRBD could be used to detect decline in striatal tracer uptake, indicating progressive nigrostriatal cell degeneration.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1474-4465
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pubmed:author |
pubmed-author:CotAlbertA,
pubmed-author:IranzoAlexA,
pubmed-author:LomeñaFranciscoF,
pubmed-author:MolinuevoJosé LuisJL,
pubmed-author:PavíaJavierJ,
pubmed-author:RosDomènecD,
pubmed-author:SalameroManelM,
pubmed-author:SantamariaJoanJ,
pubmed-author:SerradellMónicaM,
pubmed-author:TolosaEduardoE,
pubmed-author:ValldeoriolaFrancescF
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
797-805
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pubmed:meshHeading |
pubmed-meshheading:21802993-Aged,
pubmed-meshheading:21802993-Cohort Studies,
pubmed-meshheading:21802993-Corpus Striatum,
pubmed-meshheading:21802993-Dopamine Plasma Membrane Transport Proteins,
pubmed-meshheading:21802993-Female,
pubmed-meshheading:21802993-Follow-Up Studies,
pubmed-meshheading:21802993-Humans,
pubmed-meshheading:21802993-Male,
pubmed-meshheading:21802993-Middle Aged,
pubmed-meshheading:21802993-Prospective Studies,
pubmed-meshheading:21802993-REM Sleep Behavior Disorder,
pubmed-meshheading:21802993-Substantia Nigra,
pubmed-meshheading:21802993-Time Factors,
pubmed-meshheading:21802993-Tomography, Emission-Computed, Single-Photon
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pubmed:year |
2011
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pubmed:articleTitle |
Serial dopamine transporter imaging of nigrostriatal function in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a prospective study.
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pubmed:affiliation |
Neurology Service, Hospital Clinic, Barcelona, Spain. airanzo@clinic.ub.es
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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