|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0011155,
umls-concept:C0018133,
umls-concept:C0039194,
umls-concept:C0085358,
umls-concept:C0127400,
umls-concept:C0281604,
umls-concept:C1141628,
umls-concept:C1280500,
umls-concept:C1292733,
umls-concept:C1332717,
umls-concept:C1413244,
umls-concept:C1706438,
umls-concept:C2698600
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2011-7-22
|
|
pubmed:abstractText |
Graft-versus-host disease (GVHD) remains the main barrier to broader application of allogeneic hematopoietic stem cell transplantation (alloSCT) as a curative therapy for host malignancy. GVHD is mediated by allogeneic T cells directed against histocompatibility antigens expressed by host tissues. Based on previous studies, we postulated that the integrin CD103 is required for CD8-mediated GVHD, but not for graft-versus-tumor effects (GVT).
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-11965233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-12909456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-1531413,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-15897278,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-16517706,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-16641398,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-17325197,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-19047166,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-19282026,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-19638592,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-19645708,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-2142440,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-2242756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-7745114,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-7964446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-8240824,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-8291119,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-8963063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-9743533,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21779359-9820507
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1932-6203
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
6
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
e21968
|
|
pubmed:meshHeading |
pubmed-meshheading:21779359-Animals,
pubmed-meshheading:21779359-Antigens, CD,
pubmed-meshheading:21779359-CD8-Positive T-Lymphocytes,
pubmed-meshheading:21779359-Flow Cytometry,
pubmed-meshheading:21779359-Graft vs Host Disease,
pubmed-meshheading:21779359-Graft vs Tumor Effect,
pubmed-meshheading:21779359-Integrin alpha Chains,
pubmed-meshheading:21779359-Isoantigens,
pubmed-meshheading:21779359-Mice,
pubmed-meshheading:21779359-Mice, Inbred BALB C,
pubmed-meshheading:21779359-Mice, Inbred C57BL
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
CD103 deficiency prevents graft-versus-host disease but spares graft-versus-tumor effects mediated by alloreactive CD8 T cells.
|
|
pubmed:affiliation |
Department of Microbiology and Immunology, University of Maryland Medical School, Baltimore, Maryland, United States of America.
|
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|
