| pubmed-article:2170675 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2170675 | lifeskim:mentions | umls-concept:C0019351 | lld:lifeskim |
| pubmed-article:2170675 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:2170675 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:2170675 | lifeskim:mentions | umls-concept:C0040995 | lld:lifeskim |
| pubmed-article:2170675 | lifeskim:mentions | umls-concept:C0872054 | lld:lifeskim |
| pubmed-article:2170675 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:2170675 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:2170675 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:2170675 | pubmed:dateCreated | 1990-11-15 | lld:pubmed |
| pubmed-article:2170675 | pubmed:abstractText | Using a cornea trigeminal ganglion model, we have investigated transcription by herpes simplex virus type 2 (HSV-2) during latency in mice. Latency was verified 2 months postinoculation by reactivation of HSV-2 after explant cocultivation of trigeminal ganglia from the majority of mice (83%). Transcription during latent HSV-2 infection was limited to the repeat regions of the viral genome as determined by in situ hybridization using restriction fragment probes representing 100% of the HSV-2 genome. Further mapping of the positively hybridizing region by using subfragments showed that transcription occurred from approximately 11.5 kb of contiguous DNA fragments. A 1.0-kb PvuI-BamHI fragment within the BamHI F fragment and a 0.3-kb BamHI-SalI fragment and a 3.4-kb SalI-BamHI fragment within the BamHI P fragment hybridized more strongly than other subfragments in in situ hybridization experiments. All positive signals were confined to the nucleus. The RNA that hybridized to the 3.4-kb SalI-BamHI DNA fragment probe by in situ hybridization corresponded to a 2.3-kb transcript on Northern (RNA) blots. Under our conditions for Northern blot hybridization, the 3.4-kb SalI-BamHI probe of HSV-2 hybridized to a limited degree with the latency-associated transcripts of HSV-1. Shorter spliced species of latency-associated transcript RNA, which are seen during HSV-1 latency, have not been detected in latent HSV-2 RNA. However, viral gene expression during HSV-2 latency appears to be very similar to that during HSV-1 latency. | lld:pubmed |
| pubmed-article:2170675 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2170675 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2170675 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2170675 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2170675 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:2170675 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:2170675 | pubmed:author | pubmed-author:MitchellW JWJ | lld:pubmed |
| pubmed-article:2170675 | pubmed:author | pubmed-author:McGeochD JDJ | lld:pubmed |
| pubmed-article:2170675 | pubmed:author | pubmed-author:DolanAA | lld:pubmed |
| pubmed-article:2170675 | pubmed:author | pubmed-author:FraserN WNW | lld:pubmed |
| pubmed-article:2170675 | pubmed:author | pubmed-author:DeshmaneS LSL | lld:pubmed |
| pubmed-article:2170675 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2170675 | pubmed:volume | 64 | lld:pubmed |
| pubmed-article:2170675 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2170675 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2170675 | pubmed:pagination | 5342-8 | lld:pubmed |
| pubmed-article:2170675 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:meshHeading | pubmed-meshheading:2170675-... | lld:pubmed |
| pubmed-article:2170675 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2170675 | pubmed:articleTitle | Characterization of herpes simplex virus type 2 transcription during latent infection of mouse trigeminal ganglia. | lld:pubmed |
| pubmed-article:2170675 | pubmed:affiliation | Wistar Institute, Philadelphia, Pennsylvania 19104-4268. | lld:pubmed |
| pubmed-article:2170675 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2170675 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2170675 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:2170675 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2170675 | lld:pubmed |
