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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1990-11-2
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pubmed:abstractText |
Recent reports have suggested that serum creatine kinase isoenzyme BB (CK-BB) may be used as a tumor marker for a variety of malignancies, particularly prostatic carcinoma. Two cases of small cell anaplastic carcinoma of the lung (SCAC) had markedly contrasting levels of CK-BB by serum electrophoresis. Retrospective analysis of the index cases, and four additional autopsy cases of SCAC, included: 1) quantitation of CK-B in postmortem tumor and adjacent non-tumor lung tissue; 2) enzymatic and radioimmunoassay serum levels of CK-B; and 3) CK-B immunoperoxidase staining of tumor and non-tumor tissues for CK-B. Serum CK-BB is a non-specific tumor marker, but its presence, in whatever amount, should alert the clinician to the possibility of an associated malignancy, particularly SCAC or metastatic carcinoma.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0746-8288
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
83
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
564-7
|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2170501-Aged,
pubmed-meshheading:2170501-Carcinoma, Small Cell,
pubmed-meshheading:2170501-Creatine Kinase,
pubmed-meshheading:2170501-Female,
pubmed-meshheading:2170501-Humans,
pubmed-meshheading:2170501-Isoenzymes,
pubmed-meshheading:2170501-Lung Neoplasms,
pubmed-meshheading:2170501-Tumor Markers, Biological
|
pubmed:year |
1990
|
pubmed:articleTitle |
Serum creatine kinase-BB and small cell anaplastic carcinoma of the lung: two case reports.
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pubmed:affiliation |
Department of Pathology, Methodist Hospital, Peoria, Ill.
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pubmed:publicationType |
Journal Article,
Case Reports
|