21700583

Source:http://linkedlifedata.com/resource/pubmed/id/21700583

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002395, umls-concept:C0002716, umls-concept:C0152306, umls-concept:C0332281, umls-concept:C0392756, umls-concept:C0441655, umls-concept:C0599668, umls-concept:C2828008
pubmed:issue	1
pubmed:dateCreated	2011-7-5
pubmed:abstractText	This study examined the relationship between postmortem precuneus cholinergic enzyme activity, Pittsburgh compound B (PiB) binding, and soluble amyloid-? concentration in mild cognitive impairment (MCI) and Alzheimer disease (AD).
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AG025204, http://linkedlifedata.com/resource/pubmed/grant/AG05133, http://linkedlifedata.com/resource/pubmed/grant/AG10161, http://linkedlifedata.com/resource/pubmed/grant/AG12138, http://linkedlifedata.com/resource/pubmed/grant/AG14449
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0401060
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Amyloid, http://linkedlifedata.com/resource/pubmed/chemical/Amyloid beta-Peptides, http://linkedlifedata.com/resource/pubmed/chemical/Benzothiazoles, http://linkedlifedata.com/resource/pubmed/chemical/Choline O-Acetyltransferase, http://linkedlifedata.com/resource/pubmed/chemical/N-methyl-2-(4'-methylaminophenyl)-6-..., http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments, http://linkedlifedata.com/resource/pubmed/chemical/Tritium, http://linkedlifedata.com/resource/pubmed/chemical/amyloid beta-protein (1-42)
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1526-632X
pubmed:author	pubmed-author:AbrahamsonE EEE, pubmed-author:DeKoskyS TST, pubmed-author:IkonomovicM DMD, pubmed-author:KlunkW EWE, pubmed-author:MathisC ACA, pubmed-author:MufsonE JEJ, pubmed-author:ScheffS WSW, pubmed-author:WuuJJ
pubmed:issnType	Electronic
pubmed:day	5
pubmed:volume	77
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	39-47
pubmed:meshHeading	pubmed-meshheading:21700583-Aged, pubmed-meshheading:21700583-Aged, 80 and over, pubmed-meshheading:21700583-Alzheimer Disease, pubmed-meshheading:21700583-Amyloid, pubmed-meshheading:21700583-Amyloid beta-Peptides, pubmed-meshheading:21700583-Benzothiazoles, pubmed-meshheading:21700583-Case-Control Studies, pubmed-meshheading:21700583-Choline O-Acetyltransferase, pubmed-meshheading:21700583-Female, pubmed-meshheading:21700583-Humans, pubmed-meshheading:21700583-Male, pubmed-meshheading:21700583-Neurofibrillary Tangles, pubmed-meshheading:21700583-Parietal Lobe, pubmed-meshheading:21700583-Peptide Fragments, pubmed-meshheading:21700583-Postmortem Changes, pubmed-meshheading:21700583-Psychiatric Status Rating Scales, pubmed-meshheading:21700583-Radioligand Assay, pubmed-meshheading:21700583-Tritium
pubmed:year	2011
pubmed:articleTitle	Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease.
pubmed:affiliation	Department of Neurology, University of Pittsburgh, 200 Lothrop Street BST S521, Pittsburgh, PA 15213, USA. ikonomovicmd@upmc.edu
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural