Linked Life Data

21677244

Source:http://linkedlifedata.com/resource/pubmed/id/21677244

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-6-16
pubmed:abstractText
Endocrine changes are reported in both epilepsy and depression. The interrelationships between mood, epilepsy, and endocrine changes are not well characterized. The authors included 40 epileptic patients (20 depressed, 20 nondepressed) and 20 healthy subjects. All patients had an electroencephalogram, and were given the Hamilton Rating Scale for Depression. All subjects were tested for serum levels of cortisol, prolactin, testosterone, and thyroid hormones. Patients were medication-free. Patients had elevated prolactin and cortisol and reduced serum testosterone relative to control subjects. Depressed patients had higher cortisol levels than nondepressed. Data suggest that the effects of epilepsy and depression on cortisol, but not other hormones, may be additive.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1545-7222
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-7
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Neuroendocrinal study of depression in male epileptic patients.
pubmed:affiliation
Department of Psychiatry and Behavioral Neurosciences, Division of Endocrinology and Metabolism, Wayne State University School of Medicine, Detroit, MI, and the Department of Neuropsychiatry, Faculty of Medicine, Tanta University, Egypt. safifi@med.wayne.edu
pubmed:publicationType
Journal Article