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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-9-26
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pubmed:abstractText |
We have investigated the possible interaction of Japanese Kampo medicine; Shosaiko-to with Epstein-Barr virus (EBV) induction by TPA (12-O-tetra-decanoyl-phorbol-13-acetate) in EBV-genome harboring cells. The effect of ether extract of Shosaiko-to was also studied on the induction of EBV by superinfection with EBV from P3HR-1 cells (P3H-EBV). Concomitant treatment of EBV-latently-infected cells (Raji and A2L/AH) with TPA and ether extract resulted in effective inhibition of EBV-antigen induction. However, in the experiments to test the influence of ether extract on EBV induction by superinfecting Raji cells with P3H-EBV, ether extract did not affect the percentage of EBV-antigen-positive cells. These data indicate that Shosaiko-to is effective to inhibit antigen synthesis induced by chemical promoters without affecting EBV-antigen induction after superinfection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Carcinogens,
http://linkedlifedata.com/resource/pubmed/chemical/Drugs, Chinese Herbal,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Extracts,
http://linkedlifedata.com/resource/pubmed/chemical/shosaiko-to
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pubmed:status |
MEDLINE
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pubmed:issn |
0385-8146
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
49-54
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pubmed:dateRevised |
2002-12-13
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pubmed:meshHeading |
pubmed-meshheading:2167654-Antigens, Viral,
pubmed-meshheading:2167654-Capsid,
pubmed-meshheading:2167654-Carcinogens,
pubmed-meshheading:2167654-Drugs, Chinese Herbal,
pubmed-meshheading:2167654-Herpesvirus 4, Human,
pubmed-meshheading:2167654-Plant Extracts,
pubmed-meshheading:2167654-Transfection,
pubmed-meshheading:2167654-Tumor Cells, Cultured,
pubmed-meshheading:2167654-Virus Activation
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pubmed:year |
1990
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pubmed:articleTitle |
Inhibitory effects of kampo medicine on Epstein-Barr virus antigen induction by tumor promoter.
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pubmed:affiliation |
Department of Otorhinolaryngology, School of Medicine, Kanazawa University, Japan.
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pubmed:publicationType |
Journal Article
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