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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8 Pt 2
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pubmed:dateCreated |
1990-9-26
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pubmed:abstractText |
The efficacy of concentrated CDDP-Lipiodol Emulsion was experimentally and clinically studied in the treatment of nonresectable hepatoma. The commercially available CDDP was ten-fold concentrated into water in oil form. The agent was administered via hepatic artery in 26 patients with nonresectable hepatocellular carcinoma. In vitro and clinical studies strongly suggested a gradual release of the CDDP into the surrounding tissue. In 9 out of 26 patients (34.6%), tumor regression was found. Side effects were minimum; mild nausea and vomiting were observed in only 13 patients. On the basis of our preliminary study, concentrated CDDP-Lipiodol emulsion promises to be a useful agent for the treatment of nonresectable hepatocellular carcinoma.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0385-0684
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1731-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2167645-Carcinoma, Hepatocellular,
pubmed-meshheading:2167645-Cisplatin,
pubmed-meshheading:2167645-Delayed-Action Preparations,
pubmed-meshheading:2167645-Emulsions,
pubmed-meshheading:2167645-Hepatic Artery,
pubmed-meshheading:2167645-Humans,
pubmed-meshheading:2167645-Infusions, Intra-Arterial,
pubmed-meshheading:2167645-Iodized Oil,
pubmed-meshheading:2167645-Liver Neoplasms,
pubmed-meshheading:2167645-Prognosis
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pubmed:year |
1990
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pubmed:articleTitle |
[Efficacy of concentrated CDDP-lipiodol emulsion for hepatic arterial infusion therapy in patients with nonresectable hepatoma].
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pubmed:affiliation |
First Dept. of Surgery, Medical College of Oita.
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pubmed:publicationType |
Journal Article,
English Abstract
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