Source:http://linkedlifedata.com/resource/pubmed/id/21676452
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2011-8-8
|
| pubmed:abstractText |
Secretory leukocyte protease inhibitor (SLPI) is amplified in serous ovarian cancer. We have dissected its function, showing it is a survival factor for ovarian cancer and promotes tumorigenesis and paclitaxel-resistance. We hypothesized that the protease inhibitory function was responsible for modulating SLPI's invasive capacity.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
1095-6859
|
| pubmed:author | |
| pubmed:copyrightInfo |
Published by Elsevier Inc.
|
| pubmed:issnType |
Electronic
|
| pubmed:volume |
122
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
656-62
|
| pubmed:meshHeading |
pubmed-meshheading:21676452-Cystadenocarcinoma, Serous,
pubmed-meshheading:21676452-Female,
pubmed-meshheading:21676452-Fibrinolysin,
pubmed-meshheading:21676452-Humans,
pubmed-meshheading:21676452-Matrix Metalloproteinase 9,
pubmed-meshheading:21676452-Ovarian Neoplasms,
pubmed-meshheading:21676452-Secretory Leukocyte Peptidase Inhibitor,
pubmed-meshheading:21676452-Transcription, Genetic,
pubmed-meshheading:21676452-Transfection,
pubmed-meshheading:21676452-Up-Regulation
|
| pubmed:year |
2011
|
| pubmed:articleTitle |
Paracrine SLPI secretion upregulates MMP-9 transcription and secretion in ovarian cancer cells.
|
| pubmed:affiliation |
Molecular Signaling Section, Medical Oncology Branch, National Cancer Institute, Bethesda, MD 20892, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Intramural
|