|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003467,
umls-concept:C0020517,
umls-concept:C0034693,
umls-concept:C0184898,
umls-concept:C0205094,
umls-concept:C0205184,
umls-concept:C0443254,
umls-concept:C0598179,
umls-concept:C0600388,
umls-concept:C0851285,
umls-concept:C1527148,
umls-concept:C1879547
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2011-8-25
|
|
pubmed:abstractText |
A recent study has demonstrated that surgical incision induces an anxiety-like behavior but its relationship with incision-evoked mechanical hypersensitivity remains elusive. Extracellular signal-regulated kinase (ERK) activity in the anterior cingulate cortex (ACC) is important for the affective pain. The current study aims to explore ERK1/2 activity in the ACC and its role in the development of anxiety and mechanical hypersensitivity after incision.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
1528-1175
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
115
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
604-13
|
|
pubmed:meshHeading |
pubmed-meshheading:21670662-Animals,
pubmed-meshheading:21670662-Anxiety,
pubmed-meshheading:21670662-Behavior, Animal,
pubmed-meshheading:21670662-Blotting, Western,
pubmed-meshheading:21670662-Butadienes,
pubmed-meshheading:21670662-Enzyme Activation,
pubmed-meshheading:21670662-Enzyme Inhibitors,
pubmed-meshheading:21670662-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:21670662-Flavonoids,
pubmed-meshheading:21670662-Foot,
pubmed-meshheading:21670662-Gyrus Cinguli,
pubmed-meshheading:21670662-Hyperalgesia,
pubmed-meshheading:21670662-Immunohistochemistry,
pubmed-meshheading:21670662-Male,
pubmed-meshheading:21670662-Motor Activity,
pubmed-meshheading:21670662-Nitriles,
pubmed-meshheading:21670662-Pain, Postoperative,
pubmed-meshheading:21670662-Pain Measurement,
pubmed-meshheading:21670662-Phosphorylation,
pubmed-meshheading:21670662-Physical Stimulation,
pubmed-meshheading:21670662-Rats,
pubmed-meshheading:21670662-Rats, Sprague-Dawley
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Biphasic activation of extracellular signal-regulated kinase in anterior cingulate cortex distinctly regulates the development of pain-related anxiety and mechanical hypersensitivity in rats after incision.
|
|
pubmed:affiliation |
Department of Anesthesia, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China. ruping_dai@yahoo.com.cn
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
