Linked Life Data

21668823

Source:http://linkedlifedata.com/resource/pubmed/id/21668823

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-8-11
pubmed:abstractText
Rotaviruses are the cause of acute gastroenteritis, and disease is widespread amongst infants and young children throughout the world. Also, rotavirus is associated with significant mortality in developing countries with more than 500 000 children dying each year as a result of the severe dehydration associated with rotavirus disease. Efforts have been ongoing for more than 30 years to develop a safe and effective rotavirus vaccine. Currently, two vaccines, RotaRix and RotaTeq, have been licensed for use in many countries throughout the world following comprehensive safety and efficiency trials. Monitoring their effectiveness after licensure has confirmed that their incorporation into early childhood vaccination schedules can significantly prevent severe rotavirus diarrhoea, which would have resulted in hospitalizations, emergency room visits or increased diarrhoea-related mortality. Although the efficacy of both vaccines is lower at approximately 40-59% in developing countries, their use could significantly reduce the mortality associated with rotavirus disease that is concentrated in these countries.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1365-2796
pubmed:author
pubmed:copyrightInfo
© 2011 The Association for the Publication of the Journal of Internal Medicine.
pubmed:issnType
Electronic
pubmed:volume
270
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
206-14
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Rotavirus vaccines: safety, efficacy and public health impact.
pubmed:affiliation
Specialist Virology Centre, Microbiology, Norfolk and Norwich University Hospital, Norwich, UK. james.gray@nnuh.nhs.uk
pubmed:publicationType
Journal Article