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rdf:type |
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lifeskim:mentions |
umls-concept:C0086597,
umls-concept:C0086982,
umls-concept:C0205098,
umls-concept:C0221464,
umls-concept:C0699794,
umls-concept:C1336645,
umls-concept:C1367028,
umls-concept:C1412836,
umls-concept:C1420805,
umls-concept:C1533591,
umls-concept:C1710303
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pubmed:issue |
8
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pubmed:dateCreated |
2011-7-26
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pubmed:abstractText |
The receptor activator of nuclear factor-?B (RANK), RANK ligand (RANKL), and osteoprotegerin (OPG) signaling pathway (RANKL/RANK/OPG signaling) is implicated in the osteolysis associated with diabetic Charcot neuroarthropathy (CN); however, the links with medial arterial calcification (MAC) seen in people with CN are unclear. This study aimed to investigate the role of RANKL/OPG in MAC in patients with CN.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1939-327X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2187-96
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pubmed:meshHeading |
pubmed-meshheading:21659498-Aged,
pubmed-meshheading:21659498-Calcinosis,
pubmed-meshheading:21659498-Cell Differentiation,
pubmed-meshheading:21659498-Cells, Cultured,
pubmed-meshheading:21659498-Charcot-Marie-Tooth Disease,
pubmed-meshheading:21659498-Diabetic Nephropathies,
pubmed-meshheading:21659498-Female,
pubmed-meshheading:21659498-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:21659498-Humans,
pubmed-meshheading:21659498-Interleukin-8,
pubmed-meshheading:21659498-Male,
pubmed-meshheading:21659498-Middle Aged,
pubmed-meshheading:21659498-Muscle, Smooth, Vascular,
pubmed-meshheading:21659498-Osteoprotegerin,
pubmed-meshheading:21659498-RANK Ligand,
pubmed-meshheading:21659498-Receptor Activator of Nuclear Factor-kappa B,
pubmed-meshheading:21659498-Signal Transduction
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pubmed:year |
2011
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pubmed:articleTitle |
The RANKL/RANK/OPG signaling pathway mediates medial arterial calcification in diabetic Charcot neuroarthropathy.
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pubmed:affiliation |
Department of Medicine and Diabetes, Manchester Royal Infirmary, Manchester, UK. agbor.ako@manchester.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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