Linked Life Data

2165414

Source:http://linkedlifedata.com/resource/pubmed/id/2165414

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-9-4
pubmed:abstractText
We report a case of polymorphic reticulosis (PR) associated with pharyngeal replication of Epstein-Barr virus (EBV). A 78-year-old man with necrotic inflammatory granulations in the nasal cavities and ulcerative tissue of the tonsils was found to have PR after an initial diagnosis of lethal midline granuloma and was found to have high antibody titers to EBV. EBV-determined nuclear antigen (EBNA) was demonstrated in pharyngeal biopsy specimens by the anti-complement immunofluorescent technique, following which dual immunofluorescence staining, EBNA and T-cell antigen analysis were performed, using a wide variety of monoclonal antibodies. All of the EBNA-positive lymphocytes in the pharyngeal biopsy specimens were found to have exclusively T-cell antigens. This case strongly suggests that some of the cases of PR related to T-cell lymphomas may be closely associated with active EBV infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0937-4477
pubmed:author
pubmed:issnType
Print
pubmed:volume
247
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Association of Epstein-Barr virus with polymorphic reticulosis.
pubmed:affiliation
Department of Otorhinolaryngology, School of Medicine, Kanazawa University, Japan.
pubmed:publicationType
Journal Article, Case Reports