Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-6-3
pubmed:abstractText
The major histocompatibility complex (MHC) is one of the biological systems of major polymorphisms. The study of HLA class II variability has allowed the identification of several alleles that are characteristic to Amerindian populations, and it is an excellent tool to define the relations and biological affinities among them. In this work, we analyzed the allelic distribution of the HLA-DRB1 class II locus in four Amerindian populations: Mapuche (n = 34) and Tehuelche (n = 23) from the Patagonian region of Argentina, and Wichi SV (n = 24) and Lengua (n = 17) from the Argentinean and Paraguayan Chaco regions, respectively. In all of these groups, relatively high frequencies of Amerindian HLA-DRB1 alleles were observed (DRB1*0403, DRB1*0407, DRB1*0411, DRB1*0417, DRB1*0802, DRB1*0901, DRB1*1402, DRB1*1406 and DRB1*1602). However, we also detected the presence of non-Amerindian variants in Mapuche (35%) and Tehuelche (22%). We compared our data with those obtained in six indigenous groups of the Argentinean Chaco region and in a sample from Buenos Aires City. The genetic distance dendrogram showed a clear-cut division between the Patagonian and Chaco populations, which formed two different clusters. In spite of their linguistic differences, it can be inferred that the biological affinities observed are in concordance with the geographic distributions and interethnic relations established among the groups studied.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-10600013, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-11385600, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-11505474, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-11543902, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-12098752, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-1293085, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-14617035, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-1637966, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-3447015, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-3862647, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-4519626, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-6584704, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-6701886, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-7476138, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-8300406, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-8406622, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-8896175, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-9331946, http://linkedlifedata.com/resource/pubmed/commentcorrection/21637670-9490295
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Apr
pubmed:issn
1415-4757
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
212-9
pubmed:dateRevised
2011-7-28
pubmed:year
2009
pubmed:articleTitle
HLA-DRB1 alleles in four Amerindian populations from Argentina and Paraguay.
pubmed:affiliation
Sección Antropología Biológica, Instituto de Ciencias Antropológicas, Facultad de Filosofía y Letras, Universidad de Buenos Aires, Buenos Aires Argentina.
pubmed:publicationType
Journal Article