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rdf:type |
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lifeskim:mentions |
umls-concept:C0037083,
umls-concept:C0042172,
umls-concept:C0086418,
umls-concept:C0246473,
umls-concept:C0596290,
umls-concept:C0699790,
umls-concept:C1314939,
umls-concept:C1420644,
umls-concept:C1518174,
umls-concept:C1705000,
umls-concept:C1710082
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pubmed:issue |
5
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pubmed:dateCreated |
2011-5-31
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pubmed:abstractText |
Colon cancers are the frequent causes of cancer mortality worldwide. Recently bacterial toxins have received marked attention as promising approaches in the treatment of colon cancer. Thermostable direct hemolysin (TDH) secreted by Vibrio parahaemolyticus causes influx of extracellular calcium with the subsequent rise in intracellular calcium level in intestinal epithelial cells and it is known that calcium has antiproliferative activity against colon cancer.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-10024554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-10335805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-10385618,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-10495432,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-10668488,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-10816461,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-10837003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-10966228,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-11179658,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-11267998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-11413485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-11560998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-11710734,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-12393814,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-12594332,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-12914697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-14520351,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-1475518,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-16264270,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-18725175,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-2831446,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-7772641,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/21625458-9689134
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e20098
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pubmed:meshHeading |
pubmed-meshheading:21625458-Base Sequence,
pubmed-meshheading:21625458-Basic Helix-Loop-Helix Leucine Zipper Transcription Factors,
pubmed-meshheading:21625458-Cadherins,
pubmed-meshheading:21625458-Cell Line, Tumor,
pubmed-meshheading:21625458-Colonic Neoplasms,
pubmed-meshheading:21625458-DNA Primers,
pubmed-meshheading:21625458-Down-Regulation,
pubmed-meshheading:21625458-Hemolysin Proteins,
pubmed-meshheading:21625458-Humans,
pubmed-meshheading:21625458-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21625458-Signal Transduction,
pubmed-meshheading:21625458-Transcription Factors,
pubmed-meshheading:21625458-beta Catenin
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pubmed:year |
2011
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pubmed:articleTitle |
Thermostable direct hemolysin downregulates human colon carcinoma cell proliferation with the involvement of E-cadherin, and ?-catenin/Tcf-4 signaling.
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pubmed:affiliation |
Division of Pathophysiology, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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