| pubmed-article:21625377 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C0279516 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C0021102 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C1704229 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C1705604 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C0439834 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C1697272 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C1522408 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C1704806 | lld:lifeskim |
| pubmed-article:21625377 | lifeskim:mentions | umls-concept:C1143374 | lld:lifeskim |
| pubmed-article:21625377 | pubmed:dateCreated | 2011-5-31 | lld:pubmed |
| pubmed-article:21625377 | pubmed:abstractText | Madurahydroxylactone (MHL), a secondary metabolite with antibacterial activity was evaluated for its suitability to generate controlled drug release coatings on medical implant materials. A smooth and firmly attached layer could be produced from a precursor solution on various metallic implant materials. In physiological salt solutions these coatings dissolved within a time period up to one week. A combination of MHL with a broad spectrum fluoroquinolone antibiotic was used to create a coating that was active against all bacterial strains tested. The time period during which the coating remained active against Pseudomonas aeruginosa was investigated. The results indicated a delayed drug release from single layer coatings in the course of seven days. MHL was biocompatible in cell culture assays and could after a delay even serve as a cell adhesion substrate for human or murine cells. The findings indicate a potential for MHL for the generation of delayed release antimicrobial implant coatings. | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21625377 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21625377 | pubmed:status | PubMed-not-MEDLINE | lld:pubmed |
| pubmed-article:21625377 | pubmed:issn | 1874-1207 | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:NimtzManfredM | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:HauserHansjör... | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:MuellerPeter... | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:MöllmannUteU | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:LenarzThomasT | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:Schnabelrauch... | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:VogtSebastian... | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:StieveMartinM | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:StieschMeikeM | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:BadarMuhammad... | lld:pubmed |
| pubmed-article:21625377 | pubmed:author | pubmed-author:HemmenKatheri... | lld:pubmed |
| pubmed-article:21625377 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21625377 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:21625377 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21625377 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21625377 | pubmed:pagination | 263-70 | lld:pubmed |
| pubmed-article:21625377 | pubmed:dateRevised | 2011-7-28 | lld:pubmed |
| pubmed-article:21625377 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:21625377 | pubmed:articleTitle | Evaluation of madurahydroxylactone as a slow release antibacterial implant coating. | lld:pubmed |
| pubmed-article:21625377 | pubmed:affiliation | Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany. | lld:pubmed |
| pubmed-article:21625377 | pubmed:publicationType | Journal Article | lld:pubmed |
