Source:http://linkedlifedata.com/resource/pubmed/id/21623392
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2011-6-6
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pubmed:abstractText |
Glucose stimulates insulin secretion from pancreatic islet ? cells by altering ion channel activity and membrane potential in the ? cells. TRPV1 channel is expressed in the ? cells and capsaicin induces insulin secretion similarly to glucose. This study aims to investigate the biophysical properties of the ? cells upon stimulation of membrane channels using an atomic force microscopic (AFM) nanoindentation system.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1745-7254
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
853-60
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pubmed:meshHeading |
pubmed-meshheading:21623392-Animals,
pubmed-meshheading:21623392-Biomechanics,
pubmed-meshheading:21623392-Capsaicin,
pubmed-meshheading:21623392-Cell Line, Tumor,
pubmed-meshheading:21623392-Cell Membrane,
pubmed-meshheading:21623392-Cell Size,
pubmed-meshheading:21623392-Cytoskeleton,
pubmed-meshheading:21623392-Dose-Response Relationship, Drug,
pubmed-meshheading:21623392-Glucose,
pubmed-meshheading:21623392-Insulin-Secreting Cells,
pubmed-meshheading:21623392-Membrane Potentials,
pubmed-meshheading:21623392-Microscopy, Atomic Force,
pubmed-meshheading:21623392-TRPV Cation Channels
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pubmed:year |
2011
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pubmed:articleTitle |
Nanomechanical analysis of insulinoma cells after glucose and capsaicin stimulation using atomic force microscopy.
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pubmed:affiliation |
College of Engineering, Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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