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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1990-3-12
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pubmed:abstractText |
A rare case of hepatoblastoma originating in the caudate lobe was treated successfully with intraarterial chemotherapy followed by extensive lobectomy of the left side of the liver. Imaging modalities demonstrated a solitary huge tumor, initially inoperable, occupying almost the entire liver in a 4-month-old female infant. Transcatheter intrahepatic arterial chemotherapy with 10 mg doxorubicin, 20 mg cisplatin, and 3 ml Lipiodol, repeated twice at a 1-month interval, led to a remarkable reduction in tumor size and thereby made it resectable. The volume ratio between the intact hepatic parenchyma and the tumor changed from 1:1.70 to 1:0.13, as assessed by serial computed tomography scans, and the patient's initial alpha-fetoprotein level of 223,210 ng/ml declined to 53 ng/ml. The present case is the first in the literature, to our knowledge, of a resected hepatoblastoma in the caudate lobe. Clinical details of the tumor and surgical issues are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0039-6060
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
231-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2154056-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:2154056-Carcinoma, Hepatocellular,
pubmed-meshheading:2154056-Cisplatin,
pubmed-meshheading:2154056-Combined Modality Therapy,
pubmed-meshheading:2154056-Doxorubicin,
pubmed-meshheading:2154056-Female,
pubmed-meshheading:2154056-Humans,
pubmed-meshheading:2154056-Infant,
pubmed-meshheading:2154056-Infusions, Intra-Arterial,
pubmed-meshheading:2154056-Iodized Oil,
pubmed-meshheading:2154056-Liver Neoplasms,
pubmed-meshheading:2154056-Tomography, X-Ray Computed
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pubmed:year |
1990
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pubmed:articleTitle |
Resection after intraarterial chemotherapy of a hepatoblastoma originating in the caudate lobe.
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pubmed:affiliation |
Department of Surgery, National Cancer Center Hospital, Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|