Linked Life Data

21528882

Source:http://linkedlifedata.com/resource/pubmed/id/21528882

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2011-6-10
pubmed:abstractText
The skeleton of the stemona alkaloid, stenine, has been synthesized starting from pyrrole, employing an asymmetric organocatalyzed cyclization, Sonogashira coupling, a diastereoselective intramolecular propargylic Barbier reaction, cyclocarbonylation, and diastereoselective alkene reduction. Modulation of the electron-rich nature of the pyrrole nucleus by employing an ?-trifluoroacetyl group is essential. The ?-trifluoroacetyl group may be rapidly removed under carefully defined, mild conditions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1520-6904
pubmed:author
pubmed:issnType
Electronic
pubmed:day
17
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5026-35
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Synthesis of the stenine ring system from pyrrole.
pubmed:affiliation
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371. roderick@ntu.edu.sg
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't