21510906

Source:http://linkedlifedata.com/resource/pubmed/id/21510906

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008546, umls-concept:C0019704, umls-concept:C0178539, umls-concept:C0178555, umls-concept:C0917728, umls-concept:C1335268, umls-concept:C1704675
pubmed:dateCreated	2011-5-20
pubmed:abstractText	Chromatin binding plays a central role in the molecular mechanism of LEDGF/p75 in HIV-1 DNA integration. Conflicting results have been reported in regards to the relevance of the LEDGF/p75 chromatin binding element PWWP domain in its HIV-1 cofactor activity.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/1SC2GM082301-01, http://linkedlifedata.com/resource/pubmed/grant/2R25GM069621-05, http://linkedlifedata.com/resource/pubmed/grant/5G12RR008124
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101216893
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Chromatin, http://linkedlifedata.com/resource/pubmed/chemical/HIV Integrase, http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides..., http://linkedlifedata.com/resource/pubmed/chemical/Mutant Proteins, http://linkedlifedata.com/resource/pubmed/chemical/lens epithelium-derived growth..., http://linkedlifedata.com/resource/pubmed/chemical/p31 integrase protein, Human...
pubmed:status	MEDLINE
pubmed:issn	1742-4690
pubmed:author	pubmed-author:AstiazaranPaulinaP, pubmed-author:BuenoMurilo TdMT, pubmed-author:Garcia-RiveraJose AJA, pubmed-author:KugelmanJeffrey RJR, pubmed-author:LlanoManuelM, pubmed-author:MoralesElisaE
pubmed:issnType	Electronic
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	27
pubmed:meshHeading	pubmed-meshheading:21510906-Cell Line, pubmed-meshheading:21510906-Chromatin, pubmed-meshheading:21510906-HIV Integrase, pubmed-meshheading:21510906-HIV-1, pubmed-meshheading:21510906-Humans, pubmed-meshheading:21510906-Intercellular Signaling Peptides and Proteins, pubmed-meshheading:21510906-Mutant Proteins, pubmed-meshheading:21510906-Protein Binding, pubmed-meshheading:21510906-Protein Interaction Domains and Motifs, pubmed-meshheading:21510906-Protein Interaction Mapping, pubmed-meshheading:21510906-Sequence Deletion, pubmed-meshheading:21510906-Virus Integration
pubmed:year	2011
pubmed:articleTitle	HIV-1 integrase modulates the interaction of the HIV-1 cellular cofactor LEDGF/p75 with chromatin.
pubmed:affiliation	Department of Biological Sciences, University of Texas at El Paso, 500 West University Ave, El Paso, TX 79968, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural