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rdf:type |
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lifeskim:mentions |
umls-concept:C0013081,
umls-concept:C0015677,
umls-concept:C0015696,
umls-concept:C0023895,
umls-concept:C0034693,
umls-concept:C0332281,
umls-concept:C0598608,
umls-concept:C1156853,
umls-concept:C1314792,
umls-concept:C1518422,
umls-concept:C1704259,
umls-concept:C1705987
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pubmed:dateCreated |
2011-5-18
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pubmed:abstractText |
Hyperhomocysteinemia (HHcy) causes increased oxidative stress and is an independent risk factor for cardiovascular disease. Oxidative stress is now believed to be a major contributory factor in the development of non alcoholic fatty liver disease, the most common liver disorder worldwide. In this study, the changes which occur in homocysteine (Hcy) metabolism in high fat-diet induced non alcoholic fatty liver disease (NAFLD) in rats were investigated.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-12184808,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-13428781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-14556645,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-14720121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-15454290,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-15466479,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-15723740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-15890029,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-16105135,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-16108837,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-16612386,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-16936261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-16970951,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-17049925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-17855068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-17956306,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-19056644,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-19359149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-19449439,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-19592219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-19783528,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-4786524,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-4811988,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-4954368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-6137189,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-7878023,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-8561063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-8855191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-942051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21504583-9931056
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1476-511X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
60
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21504583-Animals,
pubmed-meshheading:21504583-Cystathionine beta-Synthase,
pubmed-meshheading:21504583-Cystathionine gamma-Lyase,
pubmed-meshheading:21504583-Dietary Fats,
pubmed-meshheading:21504583-Down-Regulation,
pubmed-meshheading:21504583-Fatty Liver,
pubmed-meshheading:21504583-Homocysteine,
pubmed-meshheading:21504583-Hyperhomocysteinemia,
pubmed-meshheading:21504583-Insulin,
pubmed-meshheading:21504583-Liver,
pubmed-meshheading:21504583-Male,
pubmed-meshheading:21504583-Metabolic Networks and Pathways,
pubmed-meshheading:21504583-Methyltransferases,
pubmed-meshheading:21504583-Rats,
pubmed-meshheading:21504583-Rats, Wistar,
pubmed-meshheading:21504583-Transcription, Genetic,
pubmed-meshheading:21504583-Triglycerides
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pubmed:year |
2011
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pubmed:articleTitle |
High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway.
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pubmed:affiliation |
Department of Cellular Biology and Neuroscience, Istituto Superiore Sanità, Rome, Italy. elena.bravo@iss.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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