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21498392
Source:
http://linkedlifedata.com/resource/pubmed/id/21498392
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0006826
,
umls-concept:C0521447
,
umls-concept:C0683140
,
umls-concept:C1517058
pubmed:issue
10
pubmed:dateCreated
2011-5-17
pubmed:abstractText
To determine the mechanisms by which tumors situated in extrahepatic sites can cause profound changes in hepatic drug clearance, contributing to altered drug response and chemotherapy resistance.
pubmed:grant
http://linkedlifedata.com/resource/pubmed/grant/
,
http://linkedlifedata.com/resource/pubmed/grant/P42 ES10337
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A
,
http://linkedlifedata.com/resource/pubmed/chemical/Pharmaceutical Preparations
,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1078-0432
pubmed:author
pubmed-author:ClarkeStephen JSJ
,
pubmed-author:DownesMichael RMR
,
pubmed-author:EvansRonald MRM
,
pubmed-author:KacevskaMarinaM
,
pubmed-author:LiddleChristopherC
,
pubmed-author:RobertsonGraham RGR
,
pubmed-author:SharmaRohiniR
pubmed:copyrightInfo
©2011 AACR.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3170-80
pubmed:meshHeading
pubmed-meshheading:21498392-Animals
,
pubmed-meshheading:21498392-Cell Line, Tumor
,
pubmed-meshheading:21498392-Cytochrome P-450 CYP3A
,
pubmed-meshheading:21498392-Down-Regulation
,
pubmed-meshheading:21498392-Gene Expression Profiling
,
pubmed-meshheading:21498392-Gene Expression Regulation, Neoplastic
,
pubmed-meshheading:21498392-Lac Operon
,
pubmed-meshheading:21498392-Liver
,
pubmed-meshheading:21498392-Male
,
pubmed-meshheading:21498392-Metabolic Detoxication, Drug
,
pubmed-meshheading:21498392-Mice
,
pubmed-meshheading:21498392-Mice, Transgenic
,
pubmed-meshheading:21498392-Neoplasms
,
pubmed-meshheading:21498392-Pharmaceutical Preparations
,
pubmed-meshheading:21498392-Receptors, Cytoplasmic and Nuclear
,
pubmed-meshheading:21498392-Sarcoma, Experimental
pubmed:year
2011
pubmed:articleTitle
Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism.
pubmed:affiliation
Storr Liver Unit, Westmead Millennium Institute, University of Sydney, Westmead, New South Wales, Australia.
pubmed:publicationType
Journal Article
,
Research Support, Non-U.S. Gov't
,
Research Support, N.I.H., Extramural