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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-5-25
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pubmed:abstractText |
Embryonic stem cells (ESC) and induced pluripotent stem cells (iPSCs) present a great opportunity to treat and model human disease as a cell replacement therapy. There is a growing pressure to understand better the signal transduction pathways regulating pluripotency and self-renewal of these special cells in order to deliver a safe and reliable cell based therapy in the near future. Many signal transduction pathways converge on two major cell functions associated with self-renewal and pluripotency: control of the cell cycle and apoptosis, although a standard method is lacking across the field. Here we present a detailed protocol to assess the cell cycle and apoptosis of ESC and iPSCs as a single reference point offering an easy to use standard approach across the field.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-11768996,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-12447695,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-14724578,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-16904174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-16972248,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-17142847,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-17406238,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-17406239,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-18035408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-18770651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-18983962,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-19592082,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-19658154,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-19668186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-19668188,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-19668189,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-19668190,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-19668191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-20224565,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-20231315,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21481269-9804556
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pubmed:language |
eng
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pubmed:journal |
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pubmed:status |
PubMed-not-MEDLINE
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pubmed:issn |
1478-811X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
8
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pubmed:dateRevised |
2011-9-2
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pubmed:year |
2011
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pubmed:articleTitle |
A protocol to assess cell cycle and apoptosis in human and mouse pluripotent cells.
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pubmed:affiliation |
Center of Regenerative Medicine in Barcelona, Dr, Aiguader 88, 08003 Barcelona, Spain. belmonte@salk.edu.
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pubmed:publicationType |
Journal Article
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