Source:http://linkedlifedata.com/resource/pubmed/id/21476517
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
2011-4-29
|
| pubmed:abstractText |
A convergent synthesis of the CDEF-tetracyclic region of pectenotoxin-2 (PTX-2) is described. The synthetic pathway derives from a head-to-tail union of 2 equiv of linalool to establish a stereodefined DEF-tricyclic aldehyde. Subsequent coupling with a "northern" fragment enolate, followed by a tandem Sharpless epoxidation/cyclization, delivers the C10-C26 polycyclic region of the natural product.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
1523-7052
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:day |
6
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2384-7
|
| pubmed:dateRevised |
2011-9-26
|
| pubmed:meshHeading | |
| pubmed:year |
2011
|
| pubmed:articleTitle |
A convergent route to the CDEF-tetracycle of pectenotoxin-2.
|
| pubmed:affiliation |
Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States.
|
| pubmed:publicationType |
Journal Article
|