Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2011-4-8
pubmed:abstractText
This chapter provides a succinct summary of the nephrotoxic effects of a number of metals/metalloids on an individual or mixture basis. There is a discussion of routes of exposure, mechanisms of uptake by renal cells and the potential impact of nanomaterials on these processes. An emphasis is placed on the toxicity of these metals/ metalloids to individual cell types in the kidney and the application of biomarkers for the early detection of kidney cell injury prior to the onset of an overt clinical state such as end-stage renal disease. The issue of interactions between nephrotoxic metals in mixture exposures is discussed in relation to the application of molecular biomarkers for early detection of renal cell injury.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1559-0836
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-41
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Metal ions affecting the kidney.
pubmed:affiliation
Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta GA 30341, USA. bfowler@cdc.gov
pubmed:publicationType
Journal Article, Review