|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2011-6-16
|
|
pubmed:abstractText |
We previously described a two-antibody model of (64)Cu radioimmunotherapy to evaluate low-dose, solid-tumor response. This model was designed to test the hypothesis that cellular internalization is critical in causing tumor cell death by mechanisms in addition to radiation damage. The purpose of the present study was to estimate radiation dosimetry for both antibodies (mAbs) using positron emission tomography (PET) imaging, and evaluate the effect of internalization on tumor growth.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1555-8576
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
15
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1001-7
|
|
pubmed:meshHeading |
pubmed-meshheading:21464612-Animals,
pubmed-meshheading:21464612-Antibodies, Monoclonal,
pubmed-meshheading:21464612-Cell Line, Tumor,
pubmed-meshheading:21464612-Colonic Neoplasms,
pubmed-meshheading:21464612-Copper Radioisotopes,
pubmed-meshheading:21464612-Female,
pubmed-meshheading:21464612-Humans,
pubmed-meshheading:21464612-Mice,
pubmed-meshheading:21464612-Mice, Nude,
pubmed-meshheading:21464612-Positron-Emission Tomography,
pubmed-meshheading:21464612-Radioimmunotherapy,
pubmed-meshheading:21464612-Survival Analysis,
pubmed-meshheading:21464612-Tissue Distribution,
pubmed-meshheading:21464612-Tumor Burden,
pubmed-meshheading:21464612-Xenograft Model Antitumor Assays
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Monoclonal antibodies for copper-64 PET dosimetry and radioimmunotherapy.
|
|
pubmed:affiliation |
Department of Veterinary Medicine and Surgery, University of Missouri-Columbia, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
