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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-6-13
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pubmed:abstractText |
Heart failure is a common antecedent to atrial fibrillation; both heart failure and atrial fibrillation are associated with increased myocardial oxidative stress. Chronic canine heart failure reduces atrial action potential duration and atrial refractoriness. We hypothesized that inducible nitric oxide synthase 2 (NOS2) contributes to atrial oxidative stress and electrophysiologic alterations.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1755-3245
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pubmed:author |
pubmed-author:BonillaIngridI,
pubmed-author:CardounelArturo JAJ,
pubmed-author:CarnesCynthia ACA,
pubmed-author:EltonTerry STS,
pubmed-author:EschJ FJF,
pubmed-author:GyörkeSandorS,
pubmed-author:KhanMahmoodM,
pubmed-author:KuppusamyPeriannanP,
pubmed-author:NishijimaYoshinoriY,
pubmed-author:SridharArunA,
pubmed-author:TerentyevDmitryD,
pubmed-author:TerentyevaRadmilaR,
pubmed-author:VelayuthamMurugesanM,
pubmed-author:ZweierJay LJL
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-9
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pubmed:meshHeading |
pubmed-meshheading:21460065-Action Potentials,
pubmed-meshheading:21460065-Animals,
pubmed-meshheading:21460065-Arginine,
pubmed-meshheading:21460065-Atrial Fibrillation,
pubmed-meshheading:21460065-Atrial Function, Left,
pubmed-meshheading:21460065-Biopterin,
pubmed-meshheading:21460065-Cardiac Pacing, Artificial,
pubmed-meshheading:21460065-Disease Models, Animal,
pubmed-meshheading:21460065-Dogs,
pubmed-meshheading:21460065-Female,
pubmed-meshheading:21460065-Heart Atria,
pubmed-meshheading:21460065-Heart Failure,
pubmed-meshheading:21460065-Kinetics,
pubmed-meshheading:21460065-Male,
pubmed-meshheading:21460065-Myocardium,
pubmed-meshheading:21460065-Nitric Oxide,
pubmed-meshheading:21460065-Nitric Oxide Synthase Type II,
pubmed-meshheading:21460065-Oxidative Stress,
pubmed-meshheading:21460065-Patch-Clamp Techniques,
pubmed-meshheading:21460065-Superoxides,
pubmed-meshheading:21460065-Up-Regulation,
pubmed-meshheading:21460065-Ventricular Function, Left
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pubmed:year |
2011
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pubmed:articleTitle |
Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology.
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pubmed:affiliation |
College of Pharmacy, The Ohio State University, 500 W. 12th Avenue, Columbus, OH 43210, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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