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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1990-12-27
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pubmed:abstractText |
The c-erbB-1 and c-erbB-2 proto-oncogenes are frequently activated by gene amplification and overexpression in a variety of human cancers. In an analysis of a large series of benign and malignant thyroid tumours, no abnormalities of structure or expression of either of c-erbB-1 or c-erbB-2 were found. Activation of these oncogenes is not a necessary event in neoplasia of this epithelial system.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0959-8049
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
26
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
|
pubmed:pagination |
777-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2145893-DNA, Neoplasm,
pubmed-meshheading:2145893-Gene Amplification,
pubmed-meshheading:2145893-Gene Expression,
pubmed-meshheading:2145893-Gene Rearrangement,
pubmed-meshheading:2145893-Humans,
pubmed-meshheading:2145893-Oligonucleotides,
pubmed-meshheading:2145893-Proto-Oncogenes,
pubmed-meshheading:2145893-Thyroid Neoplasms
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pubmed:year |
1990
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pubmed:articleTitle |
Absence of abnormalities of the c-erbB-1 and c-erbB-2 proto-oncogenes in human thyroid neoplasia.
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pubmed:affiliation |
ICRF Molecular Oncology Group, Hammersmith Hospital, London, U.K.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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