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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2011-6-30
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pubmed:abstractText |
Intermediate and large drusen usually precede advanced age-related macular degeneration (AMD). There is little information about which genes influence drusen accumulation. Discovery of genetic variants associated with drusen may lead to prevention and treatments of AMD in its early stages.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
1552-5783
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4663-70
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pubmed:dateRevised |
2011-9-21
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pubmed:meshHeading |
pubmed-meshheading:21447678-ATP-Binding Cassette Transporters,
pubmed-meshheading:21447678-Aged,
pubmed-meshheading:21447678-Aged, 80 and over,
pubmed-meshheading:21447678-Female,
pubmed-meshheading:21447678-Genetic Predisposition to Disease,
pubmed-meshheading:21447678-Genetic Variation,
pubmed-meshheading:21447678-Genotype,
pubmed-meshheading:21447678-Humans,
pubmed-meshheading:21447678-Lipase,
pubmed-meshheading:21447678-Macular Degeneration,
pubmed-meshheading:21447678-Male,
pubmed-meshheading:21447678-Optic Disk Drusen,
pubmed-meshheading:21447678-Phenotype,
pubmed-meshheading:21447678-Polymorphism, Single Nucleotide,
pubmed-meshheading:21447678-Severity of Illness Index
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pubmed:year |
2011
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pubmed:articleTitle |
Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration.
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pubmed:affiliation |
Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts Medical Center, Boston, Massachusetts, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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