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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2011-3-17
pubmed:abstractText
The need to understand cellular trafficking in vivo in situ requires the development and application of novel methodologies for cellular labeling and cell tracking. Here we applied new technologies associated with advances in molecular imaging to demonstrate the feasibility of labeling primary immune cells. We demonstrate the utility of fluorescently tagged polystyrene microspheres, MRI susceptible emulsions and cell entry peptoids. The adaptation of these labeling agents will permit cell specific delivery, diagnostic sensing and the delivery of therapeutic agents to sites of inflammation and infection.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1359-6640
pubmed:author
pubmed:issnType
Print
pubmed:volume
149
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-14; discussion 137-57
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Multi-modal molecular imaging approaches to detect primary cells in preclinical models.
pubmed:affiliation
MRC Centre for Inflammation Research, Queen's Medical Research Centre, University of Edinburgh, 47 Little France Crescent, Edinburgh, UK. kdhaliwa@staffmail.ed.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't