Linked Life Data

21412799

Source:http://linkedlifedata.com/resource/pubmed/id/21412799

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-3-17
pubmed:abstractText
Multiple surfaces contaminated with rhinovirus were detected in hotel rooms by reverse transcriptase-polymerase chain reaction (RT-PCR) following occupancy by a cold sufferer. Whether infectious rhinovirus contaminates surfaces in homes and is transferred from surfaces to fingertips through normal activities is not known. Nasal secretions from 30 subjects with new colds were tested for rhinovirus genome by RT-PCR; infectious rhinovirus was sought with tissue cultures. Each subject identified 10 sites in their home touched during the preceding 24 hr. Samples from sites were tested for rhinovirus by RT-PCR and cell culture. Later, each subject's mucus (stored at -70°C) was deposited on surfaces for testing transfer to fingertips through daily life activities such as flipping a light switch, touching the telephone keypad, and holding the telephone handset. Nasal secretions from 16/30 subjects were positive for rhinovirus by RT-PCR; 66 (41%) of 160 surfaces in homes were positive. Contaminated surfaces included doorknobs (6 positive/18 tested), refrigerator door handles (8/14), TV remote controls (5/10), and bathroom faucets (8/10). Five (19%) of 26 RT-PCR positive sites from culture positive subjects were positive in cell culture. Nasal mucus from six culture positive subjects was deposited on objects. Infectious rhinovirus was detected on 22% of fingertips following contact with objects contaminated for 1 hr; transfer dropped to 3% after 24 hr of contamination, and 0% after 48 hr. Infectious rhinovirus found on surfaces in homes of people with colds can be transferred to fingertips, but infectivity of virus in mucus declines by 24 hr after deposition.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1096-9071
pubmed:author
pubmed:copyrightInfo
Copyright © 2011 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
906-9
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Rhinovirus contamination of surfaces in homes of adults with natural colds: transfer of virus to fingertips during normal daily activities.
pubmed:affiliation
Department of Otolaryngology, University of Virginia Health System, Charlottesville, Virginia 22908-0713, USA. bw8b@virginia.edu
pubmed:publicationType
Journal Article