Linked Life Data

21412720

Source:http://linkedlifedata.com/resource/pubmed/id/21412720

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2011-3-17
pubmed:abstractText
Recent studies on patient with sporadic ALS and on in vitro and in vivo models of mendelian diseases have been addressed toward the unravelling of the mitochondrial behaviour in ALS, whether as a primarily pathogenic factor, or as a fundamental contributor to the cell death. Morphological evidence suggests mitochondria pathology in ALS and many physiological mechanisms involving these organelles appear deranged in ALS, such as energy production, apoptotic triggering, calcium homeostasis and axonal transport of mitochondria. The article briefly addresses recent advances on this field.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0003-9829
pubmed:author
pubmed:issnType
Print
pubmed:volume
149
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
113-9
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Mitochondrial disfunction as a cause of ALS.
pubmed:affiliation
Università di Roma "Sapienza" Dipartimento di Medicina Sperimentale, Istituto CSS-Mendel, Rome, Italy.
pubmed:publicationType
Journal Article, Review